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The result is that biosimilar penetration in the EU varies radically by country, product, and policy cycle far more variable than the U.S., where interchangeability designation creates a more uniform commercial playbook

Additional randomized, controlled trials that follow people over time are needed to confirm these findings, but these results are promising, said study author Edy Kornelius, MD, PhD, of Chung Shan Medical University in Taichung, Taiwan

These predispositions do not determine your exact response, but can support a more informed conversation with your provider about personalized dosing timing and expected tolerability

Alessandro et al., 2013

Fiber supplements like psyllium husk (Metamucil) can also help, but increase your water intake by at least 16 ounces daily when adding fiber to prevent impaction

Support with Diet: Eat plenty of sulfur-rich vegetables and manage oxidative stressors