Consistency is key glutathione builds up gradually in the body
Martin et al., 2007
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Glutathione synthesis tends to slow with age, a pattern researchers at Baylor College of Medicine and others have documented consistently in blood studies, which is one reason antioxidant status becomes a more common conversation after your mid-30s
In addition, 8-oxo-Gs accumulate at telomeres, where they inhibit telomerase and decrease the binding of telomeric proteins, leading to the disruption of telomere length and precluding the maintenance of chromosomal-end capping 46
Upton TJ, Zavala E, Methlie P, Kampe O, Tsagarakis S, Oksnes M, Bensing S, Vassiliadi DA, Grytaas MA, Botusan IR, Ueland G, Berinder K, Simunkova K, Balomenaki M, Margaritopoulos D, Henne N, Crossley R, Russell G, Husebye ES, Lightman SL