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Despite its known effects, the physiological role of DSIP remains unclear, partly due to the lack of identification of its gene and receptor

Increased risk of oral cancer in patients with inflammatory bowel diseases

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Another innovative biophysical therapeutic agent, S-1226, employs carbon dioxide (CO 2 )-rich air in combination with aerosolized perfluorocarbons (PFOB) to promote airway dilation, enhance mucus clearance, and improve blood oxygenation

Therefore, elimination of senescent immune cells, including those accumulating in tissues, has been proposed to improve the immune system activities