Because the ability to effectively absorb B12 decreases with age, its more common in older people - but that doesnt mean people of all ages cant have it
10.1016/j.pharmthera.2021.108044 62 LuZ.LiY.SynW
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This change appears on every routine glucose test and serves as a visible proof that the medication is engaging your physiology at a cellular level
If the body is deficient in certain amino acids (this is very common in Hashimotos due to protein malabsorption), the pollutants freed up in Phase I can become more toxic
Typically, doctors prescribe a loading dose, which involves multiple injections administered close together, followed by maintenance doses to sustain adequate B12 levels over time