Levels of thymic stromal lymphopoietin (TSLP, which triggers dendritic cells and secretion of Th2 cytokine production) and mannose Receptor C-Type 1 (CD206, which is expressed in various immunological cells) were also reduced
Reversal by cholic acid feeding
Mechanistically, mevalonate-derived isopentyl pyrophosphate is necessary for isopentylation of tRNA [Ser]Sec, which is required for efficient synthesis of the selenoprotein ferroptosis suppressor GPX4

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[DOI] [PubMed] [Google Scholar] 5.The effect of berberine on polycystic ovary syndrome patients with insulin resistance (PCOS-IR): a meta-analysis and systematic review