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Mean baseline body weight was 89.4 kg and mean baseline BMI was 31.8 kg/m 2 in enrolled patients

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For many years, metformin was the only antihyperglycemic medication proven to reduce mortality in patients with diabetes mellitus type 2 (as per the UKPDS trial)

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Moreover, periodic body composition assessment (e.g., through DXA or BIA) is advisable in order to early detect disproportionate loss of lean mass and to adapt nutritional interventions accordingly [42]

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