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So, Are B-12 Shots Effective for Weight Loss
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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result
However, the rate of discontinuation due to adverse events (gastrointestinal side effects) exceeded 50% in each dosage group compared to placebo [112]
A real discovery in recent years is a peptide called BPC-157
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