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Article 11 mins Understanding Extreme Heat: An Increasing Risk for People, Businesses and Society In the wake of record-breaking high global temperatures in 2023, the rising frequency of extreme heat due to climate change creates an urgency for the risk industry to analyze climate trends for better risk mitigation

- acetylcholine will produce a dose-dependent changes of blood pressure & heart rate (Figure 1)(Vanderah, 2024): : Low-dose intravenous acetylcholine Primarily activates muscarinic (M3) receptors on vascular endothelial cells (Gericke et al, 2011)

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