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Haas RH

The GPCR protease-activated receptor 2 (PAR2) is expressed on the luminal and basolateral side of epithelial cells and is a promiscuous sensor for a wide range of endogenous and bacterial proteases, which are known to regulate epithelial permeability and intestinal inflammation (19, 20)

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While these drugs were initially developed to manage diabetes, their increasing use for weight loss is altering consumer behavior in ways that could significantly impact the entire food supply chain

[DOI] [PubMed] [Google Scholar] 53.Coll AP, Loraine Tung YC

Discoveries made here were later confirmed in human genetic studies