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There has been a revival in the use of methylene blue (MB), together with artemisinin-based combinations, in the treatment of Plasmodium falciparum malaria, because MB also has a gametocytocidal action

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Cysteine dioxygenase catalyzes the oxidation of cysteine, which results in cysteine sulfonic acid and subsequently hypotaurine

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Conversely, the CBBBP peptide alone demonstrated a less marked effect, indicating that the primary therapeutic benefits are attributable to the DSIP component