People who should not use GLP-1s include: Pregnant people People with a personal or family history of medullary thyroid cancer People with multiple endocrine neoplasia syndrome type 2, a rare condition that affects the endocrine glands People who are hypersensitive to GLP-1 agonist drugs GLP-1 Drugs Are Lifelong Treatments Questions to Ask Your Doctor Am I a candidate for a GLP-1 weight loss drug
In a 2022 Diabetes Care study, tirzepatide went head-to-head with semaglutide in people with Type 2 diabetes
Glucagon-like peptide-1, or GLP-1, is a naturally occurring hormone produced by specialized intestinal cells called L-cells
Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (surpass-3): A randomised, open-label, parallel-group, phase 3 trial
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The net metabolic result is a favorable glucose profile combined with increased energy expenditure and enhanced hepatic fat clearance
