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It is a receptor agonist and should not replace insulin therapy in individuals who require it
Even if only a fraction of those patients sought GLP-1 treatment, insurers could face billions of dollars in additional costs
Doseresponse effects on HbA 1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial
This triple agonism strategy builds upon the remarkable clinical success of dual GLP-1/GIP agonists like tirzepatide, which have shown unprecedented weight loss efficacy, by adding a third mechanism - glucagon receptor activation - to further enhance metabolic benefits, particularly energy expenditure and hepatic fat oxidation
Retatrutide could represent the next evolution in obesity treatment
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