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After 20 weeks, a reduction in waist size was associated with a greater reduction in MACE compared to weight loss

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Rotating Injection Sites to Prevent Lipodystrophy Repeating injections to the same thigh location week after week causes the skin and fat to thicken or atrophy, creating visible lumps or depressions called lipodystrophy

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Quick Answer: Most GLP-1 receptor agonists must be refrigerated at 28C before first use, though some permit limited room temperature storage, and multi-dose pens often allow room temperature storage after opening

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