Because of this benefit, it is often used to treat patients with HIV and improve the function of their immune systems
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It functions as an essential cofactor for the transport of long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation
Thangamani S, Monasky R, Lee JK, Antharam V, HogenEsch H, Hazbun TR et al
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To develop REPAIR, the Cas13b ortholog was mutated to be catalytically dead Cas13b (dCas13b) and fused with the adenosine deaminase acting on RNA 2 (ADAR2) enzymeallowing for the replacement of adenosine (A) residues to inosine (I) residues on mRNA transcripts