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Regulating leukocyte adhesion Furthermore, SDC-1 dynamically regulates leukocyte adhesion through chemokine anchoring, offering a dual role in inflammation control [50, 51]

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Current approaches are largely restricted to experimental settings, while available inhibitors, such as non-specific antioxidants or iron chelators, exhibit limited specificity and raise safety concerns related to off-target effects and disruption of systemic iron homeostasis

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