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Cells either received 200 M TBHP alone or co-incubation with NAC, NACET, or diNAC at a range of concentrations, where 200 M had been previously demonstrated to be the maximum concentration to not significantly affect cell viability in ARPE-19 cells [25]

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PGC-1 regulates DRP1 expression by enriching in the promoter region to downregulate DRP1 expression and further inhibits mitochondrial fission ( via deacetylating and activating OPA1 (Samant et al., 2014)