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Shi J, Qiu H, Xu Q, Ma Y, Ye T, Kuang Z, Qu N, Kan C, Hou N, Han F, Sun X

This carnitine deficiency effectively starves the cells of their primary fuel source, locking the patient in a state of perpetual energetic depletion that cannot be resolved simply by resting or eating more calories

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Its three FDA approvals, proven cardiovascular benefit in the SELECT trial, oral formulation option, and extensive post-marketing data make it the reference against which all next-generation compounds must be measured

Part 1epidemiology, phenotype, and outcomes, Br J Dermatol 160:143150, 2009

doi:10.1007/s00592-013-0546-y 117