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Expression of Ngn3 directs differentiating secretory progenitors toward endocrine fate, while expression of Neurod1 directs differentiating EEC progenitors toward EECs such as L-cells

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It is a strategy that aims to support biology in a coordinated way

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Experimental investigations have explored its effects in models involving body composition, metabolic health, and cellular energy balance

Early experiments focused on its ability to support structural integrity in gastrointestinal models