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Martinotti cells Somatostatin-expressing inhibitory interneurons with a characteristic morphology that target the dendritic tufts of pyramidal cells in various cortical layers

In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition

The arginate salt isn't just a minor variant

Why Unopened BAC Water Doesn't Require Cold Storage And When That Changes Unopened bacteriostatic water vials are shelf-stable at controlled room temperature because the sealed system has no exposure to environmental contaminants

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The solution typically remains stable for 4-6 weeks