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primary completion November 2025)

Am J Physiol Heart Circ Physiol 290(2):H547H559 Drui D, Illouz F, Do C et al (2018) Expert opinion on thyroid complications of new anti-cancer therapies: tyrosine kinase inhibitors

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It was observed that the G2019S mutation in LRRK2 results in delayed mitochondrial arrest and increased phosphorylation of the RAB10 protein (at the threonine 73 site), which in turn leads to impaired PINK1/Parkin-mediated mitophagy (Wauters et al., 2020)