In doing so, GLP-1 RAs stimulate insulin release while suppressing glucagon secretion and slowing gastric emptying, ultimately reducing appetite
You typically start at a low dose of 0.8 mg and gradually increase your dosage over a period of 3090 days
Competing interests DB received presentation fees (TEVA, Novartis and Pfizer), travel fees (Allergan, TEVA, Pfizer, Abbvie and Lundbeck), advisory board fees (Novartis, Lilly, Teva, Lundbeck, Pfizer and Abbvie) and participated in clinical trials (TEVA, Lundbeck, Novartis, Lilly and Novo Nordisk Foundation) outside of the submitted work
Medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound), which mimics both GLP-1 and GIP, are synthetic versions of these hormones
Another promising direction involves dissolving microneedles, which completely degrade upon administration, eliminating the need for disposal and improving patient compliance
Retatrutide is a new weight loss treatment currently being tested in clinical trials