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Higher zinc concentrations, however, can suppress the release of other proinflammatory cytokines, such as IL-1 and TNF-, by inhibiting phosphodiesterase activity, thus modulating the inflammatory response [243]

The pharma released detailed results in June 2023 from its Phase III SURMOUNT-OSA program, demonstrating that Zepbound could significantly reduce disease severity in obese patients with moderate-to-severe OSA

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