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But the program that opened this access was built on clinical trial evidence that largely studied younger adults, with prescribing frameworks that do not include mandatory age-specific assessments for the risks that matter most in adults over 65: sarcopenia, bone density, malnutrition, and frailty

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Analysis of the L-Glu-bound crystal structure of BlGGT (PDB ID: 4OTU) suggested importance for another highly conserved residue, Asn450, located close to the binding pocket, in proper substrate orientation (Lin et al., 2016)

Bibcode:2021AqTox.23505838C