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Above all, the carnitine derivatives can be moved across intracellular barriers, so the carnitine system provides a shuttle mechanism between microsomes, peroxisomes, and mitochondria for complex lipid-synthetic and breakdown pathways 22

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Fat is lost faster than muscle, and that's the direction you want

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One key process is glutamate excitotoxicity, where a buildup of glutamate at the synapse due to reduced function of the transporter EAAT2 (also known as GLT-1) leads to overstimulation of N-methyl-D-aspartate (NMDA) receptors