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Patients should be advised to: Eat smaller, more frequent meals rather than large portions Choose bland, easily digestible foods during the initial treatment period Avoid high-fat, fried, or heavily spiced foods that may exacerbate nausea Stay well hydrated, sipping water throughout the day Limit alcohol and caffeine intake Eat slowly and chew food thoroughly Dose titration plays a crucial role in minimising side effects

Real-time quantitative polymerase chain reaction Total RNA was extracted from cells using the Trizol reagent (Takara Bio Inc, Japan) according to the manufacturers instructions

From the beginning, the goal is working on a plan for improved lifestyle and adherence to modifications that will sustain weight loss

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Buffers, such as dibasic sodium phosphate, are added to keep the pH of the solution close to the bodys natural pH level