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Eur J Clin Nutr 72 , 105111 (2018)

Deficiency is associated with increased depression risk, impaired insulin secretion, elevated inflammatory markers, and worsening of vasomotor symptoms in some but not all studies [13]

If accidental freezing occurs, discard the vial and contact your pharmacy for replacement

In line with this observation, 2-hydroxybutyrate is increasingly recognized as a biomarker of metabolic disturbances, particularly in insulin resistance and glucose intolerance 27

Several factors could compound the disappointing degree of sustained weight loss seen in our cohort