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Danon disease is a severe and penetrant genetic cardiomyopathy that affects 14% of patients with HCM and is caused by loss-of-function mutations in the LAMP2 gene

For a deeper look at the mechanism and clinical data, see our complete guide to what tesamorelin is and how it works

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POLG mutation screening should be performed in accordance with current clinical practice [seeWarnings and Precautions (5.1)]

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