metoprolol)Phase 3MAPLE-HCMPediatric oHCMPhase 2CEDAR-HCM Ulacamtencardiac myosin inhibitor / small molecule / CardiovascularHFpEFPhase 2AMBER-HFpEF Omecamtiv Mecarbilcardiac myosin activator / small molecule / CardiovascularHFrEFPhase 3COMET-HF CK-089CK-089 / fast skeletal muscle troponin activator / small molecule / NeuromuscularMuscular Dystrophy, OtherPhase 1 4assets 4assets DT-216P2DT-216P2 / FXN GAA repeat expansion / frataxin expression / GeneTAC small molecule / Genetic disease / neurologyFriedreich ataxiaPhase 1/2RESTORE-FA multiple-dose trial opened/ongoing
[2] Side effects [edit] Side effects of cannabinoids can include memory and concentration problems, bronchitis, lung infections, chronic cough, psychosis, and exacerbated mental health problems
Oncology (CIPN): Some syntheses suggest IV GSH may reduce severe neurotoxicity with platinum chemotherapy, but heterogeneity and mixed trials preclude firm recommendations without further large trials
Gastroparesis, also known as stomach paralysis, has no cure
The intention isnt to achieve maximum appetite suppression immediately, but rather to gently engage the GLP-1 pathway, reduce side effects like nausea and fatigue, and allow the body to adapt
Sprague Dawley rats weighing 200-250 grams were used for the study
