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On the mechanisms of induction of cancer-protective enzymes: a unifying proposal

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The following section presents a detailed description of the different classes of nano-carriers that can be employed in antioxidant delivery

However, in this pathway, melatonin increases the concentration and activation of ERK, a molecule that regulates protein transcription in the cell nucleus, by acting on PKA and decreasing the formation of cAMP that induces negative regulation of the expression of mitogenic proteins and the antiapoptotic gene Bcl-2 [28,30]

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