It isnt specifically approved for MC4R deficiency specifically, only for weight management and appetite control in adults and children with POMC- , PCSK1- , or LEPR- deficient obesity or those with genetically confirmed pathogenic variants, likely pathogenic variants, or variants of uncertain significance in POMC , PCSK1 , or LEPR (FDA: 2 years of age and older
Patients report less morning stiffness, reduced nighttime aching, and the ability to resume activities like climbing stairs or playing with grandchildren
Graaf Cd, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al
Pharmaceutical companies do not sell these drugs branded for obesity in lower income countries and sell these obesity drugs in only a small number of higher income countries
2 Retatrutides on-treatment average was 28.3%, compared with 22.5% for Mounjaro and 20.7% for Wegovy in their separate trials
Two truths: I like to make most of my meals at home