For tirzepatide users , this means the case for longer treatment duration or maintenance dosing is potentially even stronger than for semaglutide
That makes protein non-negotiable
Each component of MACE, being nonfatal myocardial infarction (26%) and nonfatal stroke (12%), CV death (7%) contributed to the risk reduction
Additionally, semaglutide injection formulations contain inactive ingredients (glycerin, sodium phosphate dibasic, sodium phosphate monobasic, water) that rarely trigger local reactions, but individual sensitivities vary
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