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Postgraduate Med

Patients with glutathione synthetase deficiency accumulate the dipeptide -glutamylcysteine and cysteine in fibroblasts [24]

Genetic context does not determine outcomes but may help explain why some people experience symptomatic improvement with glutathione supplementation while others show minimal response

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Increased ventricles and sulcal dilatation are a consequence of neuron degeneration within the brain