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Mold toxicity is often silent

Formation of bilirubin Occurs in the reticuloendothelial system (spleen, liver, bone marrow): * RBC breakdown haemoglobin * Haem biliverdin * Biliverdin bilirubin (unconjugated) This initial form is fat-soluble and toxic if accumulated 2

Each has its own effectiveness, absorption rate, and safety profile

70+% of MVD-affected dogs with mild enlargement will never need any medications Studies have found that as many as 70% or more of MVD-affected dogs with a murmur and mild heart enlargement, will not progress to heart failure, even it they remain unmedicated

Pi-Sunyer X, Apovian CM, McElroy SL, Dunayevich E, Acevedo LM, Greenway FL