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Theoharides TC, Alysandratos KD, Angelidou A, Delivanis DA, Sismanopoulos N, Zhang B, et al

Inhibiting the pathways improves the sensitivity to irradiation and reduces the expression of phosphorylated ATM, H2AX, p53BP-1, DNA-PKcs, and PARP-1 related to the DNA repair pathways (Figure 5)

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Endocrinology (2020) 161:bqaa093

High levels of sugar in the blood (hyperglycemia) and insulin deficiency or resistance can lead to increased oxidative stress

The increasing awareness of the utility of stapled peptides prompts a higher demand for the development and optimization of performance, which means that it is imperative to develop AI approaches as powerful assistants to achieve a higher success rate of therapeutic peptides in a much-shortened timeframe