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Elevated cortisol causes a cascade of issues including increased fat storage, muscle breakdown, immune suppression, and sleep disruption
It has been associated with increased BDNF and TrkB signaling in rodent brain studies, modulation of dopamine and serotonin systems, and gene-expression changes in ischemia models
Metabolites with mean and median peak intensities below the mass spectrometers limit of detection were removed from further analysis to ensure robust statistical comparisons between clinical groups
DOI: 10.4172/1165-158X.1000288 Copyright: 2023 Asaduzzaman, et al
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