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The main trigger for acne is fluctuating hormones, specifically the male hormone testosterone

Fibromyalgia is a chronic condition characterised by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties often referred to as 'fibro fog'

These are generally less common than GI events but important to understand

Effects on aging-related biology, cognitive performance, energy metabolism, antioxidant defense, or tissue repair (depending on the compound) are mediated through specific receptor or enzymatic pathways