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Consequently, novel anti-inflammatory therapeutic approaches are currently being evaluated in clinical trials (Haage and De Jager, 2022

Sun found that 15-HpETE-PE is a preferential recognition substrate of iPLA2, and iPLA2 can be hydrolyzed, inhibiting cell ferroptosis [42]

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The latter can be obtained as pure crystals from the mucus by extraction with dichloromethane and subsequent chromatographic purification with a 4:1 toluene-ethyl acetate mixture