fda warning letter hims & hers compounded semaglutide september 2025 issued 25 letters to telehealth companies for false and misleading claims about GLP-1 products. Unlike FDA-approved drugs, these products have not been proven to be safe, effective, or of Hims and Hers warns investors

However, three real risks exist: reduced therapeutic effect (dangerous for diabetes management), potential contamination in older opened vials, and possible immunogenic responses from aggregated peptides

Serious complications like infection or allergic reactions are rare but possible, particularly in people with allergies to bird proteins or feathers, as some hyaluronic acid products are derived from rooster combs

If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

The effects of GLP-1 infusion have also been studied on animal models of arrhythmias

investigated the effects of GIP, with or without GLP-1, on the reactivity of healthy rat -cells to glucose and GLP-1 (32), and they reported that a combination of GIP and GLP-1 at physiological concentrations increases reactivity to glucose, independent of insulin content

The supernatant was removed and cell pellets were immediately lysed and RNA was extracted using a Qiashredder extraction column (Cat