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Nevus con abundante pigmento ms abajo del corion, pero tambin con pigmento en estrato basal, no se observa claramente los ncleos y el diagnstico corresponde a nevus azul

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In heterogeneous tumor environments, achieving selective targeting of mutant p53 cells without damaging wild-type p53-dependent normal cells is a major challenge, mainly for the following reasons: some drugs targeting mutant p53 may also be toxic to wild-type p53 cells, and the complex tumor microenvironment may affect the efficacy of drugs

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