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March 19 Product: Takedas Iclusig Indication: Philadelphia chromosome-positive acute lymphoblastic leukemia Takeda scored a frontline approval for its kinase inhibitor Iclusig on Tuesday

We show that activating GLP-1 receptors (GLP-1R) in the OB stimulates insulin secretion in response to oral glucose in lean and diet-induced obese male mice

Per the Globe and Mail, Apotex's wholesale price is $78.14 for a four-week supply versus $240.48 for the brand, and telehealth providers Felix and Hims both charge $149 all-in

Structure/function claims These claims describe how nutrients affect the body, such as "protein helps build muscle." They avoid direct references to medications, but they can address GLP-1 users' concerns, such as loss of muscle mass

The resulting culture was then incubated at 37 C until the OD reached 0.6, after which the temperature was dropped to 18 C and the culture was induced by adding IPTG to a final concentration of 1 mM