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Semaglutide, a GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, does not have an established lethal dose in humans

Although the effects of these drugs were studied only for 2 weeks, they produced an average 20% body weight decrease, twice the effect of semaglutide alone

Maintenance Phase Duration and Sustainability Most patients remain on their maintenance dose indefinitely because semaglutide's benefits depend on continuous therapy

The brand label starts at 2.5 mg once a week

The dosage is fixed and is usually not changed

Brain Res Bull 164(2020):1420 Yousef MI, Abdou HM, Abd Elkader HTAEA, Hussein HK, Abou Samra WE (2020) Neuroprotective potential of Spirulina platensis against aluminium chloride-induced neural degeneration