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Additionally, the currently approved GLP-1 RA for obesity treatment are in injectable form and some people may be reluctant to consider injectable treatments [15]

or overweight if their BMI is greater than 27 accompanied by weight-related medical problems such as high blood pressure, type 2 diabetes, or high cholesterol

The IGF-1 receptor is referred to as the physiologic receptor because IGF-1 binds to it with significantly higher affinity (approximately 100 times higher) than it does to the insulin receptor

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However, these participants saw a significant reduction in blood pressure over the 12 weeks after they stopped taking the chanca piedra (3)

This is a known frustration