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Nanospheres successfully convert hydrogen peroxide into water, similar to what selenocysteine does in the human body when GPx is present

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In addition, several small molecules can indirectly activate CPT1A by acting on ACC2, including the AMPK activators metformin and AICAR (Tomita et al., 2005), and the ACC2 inhibitors TOFA and Soraphen ( However, overexpression of CPT1A may increase the FAO rate, promote cell metabolism, and accelerate cell apoptosis, which brings certain difficulties for the development of related drugs

Nichols et al., 2022