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The variables that had the most significant effect on the ICER were the discount rate (ICER range: $30,857.45-$57,117.71), the annual cost of oral semaglutide (ICER range: $32,004.67-$47,701.77), absolute therapeutic effect on systolic blood pressure (SBP) (ICER range: $35,539.79-$45,856.96), duration of treatment (ICER range: $34,536.96-$44,763.10), and HbA1c treatment effect (ICER range: $36,071.16-$455,01.91)

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Reconstituted solutions are typically held at 28C and used within the documented stability window