Homocysteine Homocysteine is another way to assess Vitamin B12 levels, it is not as specific as MMA because high homocysteine levels can also indicate a deficiency in B2, B6, folate, and B12
J Bone Joint Surg Am, 83-A Suppl 1 S31-39
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who compared metformin uptake levels and inhibiting activity on cancer cell growth in a human breast cancer cell line (BT-20) deficient in OCTs and a BT-20 cell line overexpressing organic cation transporter 3 (OCT3), OCT3-BH20 cells: OCT3 is also a predominant transporter in human breast neoplasms (241)
Full protocol with dosing, timing, and expected results
Rienks M, Carai P, van Teeffelen J, Eskens B, Verhesen W, Hemmeryckx B, Johnson DM, van Leeuwen R, Jones EA, Heymans S, Papageorgiou AP