MPN consists of tannic acid (TA) complexed with various transition metal ions, including Fe 3+ , Co 2+ , Ni 2+ , Cu 2+ , and Zn 2+ , which coat the surfaces of AuNPs to form a metal-TA network
Aside from its effects on ischemic heart disease, LC has been shown to be useful in arrhythmia, endothelial function, circulatory failure, and peripheral blood disorders (Shankar et al., 2004)
Most of the cases of ALS are sporadic (sALS) with no genetic linkage, while around 10% are associated with familial forms (fALS), presenting mutations in over 20 genes
Notably, data from an animal study have stated that MitoQ inhibited amyloid- peptide (A) induced oxidative stress, a critical component of Alzheimer's disease, and reversed early cognitive decline (Zhang et al., 2018)
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There are also no published guidelines for appropriate dosing regimens and duration of treatment
