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Alpha-lipoic acid modifies oxidative stress parameters in sickle cell trait subjects and sickle cell patients

This was the case in the clinical trials, where participants had their dose adjusted until they reached 2.5 mg dose if needed

"Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants"

These minerals, which are found in sea water, help balance biochemical enzymatic reactions in the body and support the natural production of glutathione.

Patients should proactively contact their GP or diabetes specialist nurse if they experience persistent or severe side effects at any dose, including ongoing nausea lasting beyond two weeks, repeated vomiting, severe abdominal pain, or signs of pancreatitis (severe upper abdominal pain radiating to the back)

This #ASNKidneyNews article recaps the study, its strengths, and its potential impact