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It concluded that administering oral semaglutide in the fasting state with up to 120 mL water [48], and a post-dose fasting period of at least 30 min, resulted in a clinically relevant semaglutide exposure

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In contrast, GLP-1 receptor agonists lack any established role in RA management

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However, delayed gastric emptying is also responsible for some of the most common adverse effects associated with semaglutide, including nausea, vomiting, and abdominal discomfort