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Diabetes Ther (2021) 12(1):5570

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Patients with pre-existing conditions such as chronic kidney disease, heart failure, or those taking diuretics, ACE inhibitors, or other medications affecting electrolyte balance require particularly careful monitoring

Its unhelpful to draw these comparisons

As research continues, FOXO4-DRI remains a compelling compound for ongoing laboratory investigation into senescence biology and transcriptional control mechanisms