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Natriuretic Peptides Atrial Natriuretic Peptide (ANP) and B-type natriuretic peptide (BNP), the main natriuresis hormones, are synthesized in cardiac tissue in response to stretching that occurs with increases in blood volume and function to decrease extracellular fluid volume and increase renal sodium excretion (108)

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According to trial data, discontinuation rates due to side effects were 12.2% for the 9mg dose and 18.2% for the 12mg dose

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Los resultados mostraron que el tratamiento con semaglutida 2.4 mg redujo en un 20% el riesgo de sufrir un accidente cerebrovascular, infarto o muerte por problemas cardacos durante un promedio de 39.8 meses.[ii] En Mxico, las enfermedades cardiovasculares son la principal causa de muerte

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1 Introduction Cardiovascular diseases (CVD), type 2 diabetes mellitus (T2DM), and obesity constitute a convergent triad representing a major global health burden

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